Predictive
Control of Blood Glucose Concentration in Type I Diabetic
Patients
Surekha Kamath*1, V.I.George*, Sudha
Vidyasagar**
* Dept of ICE
MIT MANIPAL,
** Dept Of Medicine K.M.C MANIPAL,
Abstract
Maintaining the glucose concentration in normoglycemic range
in Type I diabetic patients is challenging. In this study H∞
control is applied for the insulin delivery to prevent the
hyperglycemic levels in a type I diabetic patient. From a
control theory point of view, the blood glucose regulation
problem is reformulated as a tracking one. A glucose
tolerance curve (GTC) validated from several patients is
used as reference model. Simulation studies are performed on
the diabetic patient model under feedback control, which
revealed that the proposed control strategy is able to
control the blood glucose concentration well within the
acceptable limits and also able to compensate for the slow
parametric drifts.
Keywords: IDDM,
insulin modeling, Glucose insulin modeling, mathematical
modeling, H∞ control, Robust control.

BibTex:
@ARTICLE{P1160843435,
AUTHOR = {Surekha Kamath and V.I.George and
Sudha Vidyasagar},
TITLE = {Predictive
Control of Blood Glucose Concentration in Type I Diabetic
Patients},
JOURNAL = {ICGST International Journal on Bioinformatics and Medical
Engineering, BIME},
YEAR = {2008},
VOLUME = {08},
ISSUE ={1},
PAGES={39--43}
}
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