ICGST- BIME Journal

 

BIME Volume (08) - Issue (I) ICGST

Predictive Control of Blood Glucose Concentration in Type I Diabetic Patients

Surekha Kamath*1, V.I.George*, Sudha Vidyasagar**
* Dept of  ICE  MIT MANIPAL, ** Dept Of Medicine K.M.C MANIPAL,

Abstract
Maintaining the glucose concentration in normoglycemic range in Type I diabetic patients is challenging. In this study H∞ control is applied for the insulin delivery to prevent the hyperglycemic levels in a type I diabetic patient. From a control theory point of view, the blood glucose regulation problem is reformulated as a tracking one. A glucose tolerance curve (GTC) validated from several patients is used as reference model. Simulation studies are performed on the diabetic patient model under feedback control, which revealed that the proposed control strategy is able to control the blood glucose concentration well within the acceptable limits and also able to compensate for the slow parametric drifts.

Keywords: IDDM, insulin modeling, Glucose insulin modeling, mathematical modeling, H∞ control, Robust control.
 

BibTex:

@ARTICLE{P1160843435,

AUTHOR = {Surekha Kamath and V.I.George and Sudha Vidyasagar},

TITLE = {Predictive Control of Blood Glucose Concentration in Type I Diabetic Patients},

JOURNAL =  {ICGST International Journal on Bioinformatics and Medical Engineering, BIME},

YEAR = {2008},

VOLUME = {08},

ISSUE ={1},

PAGES={39--43}

}

(Full Paper, 895 KB)